Purpose: To investigate the effect of microalbuminuria (MA) on superficial vessel density (SVD), deep vessel density (DVD), and choriocapillaris vessel density (CVD) in type-2 diabetic patients.Methods: Twenty patients without diabetic retinopathy (DR) and MA (group 1), 20 patients without DR but with MA (group 2) and 30 patients with mild DR and MA (group 3) were enrolled in this prospective and cross-sectional study. SVD, DVD, and CVD of all patients were screened with optical coherence tomography angiography (OCTA). The relationships between these values and age, diabetes duration and metabolic parameters were also evaluated.Results: The whole macular SVD value was 50.15 ± 4.52 in group 1 and 47.81 ± 4.12 in group 2 (p = .04). The whole macular DVD value was 47.66 ± 2.76 in group 1, 44.37 ± 3.39 in group 3 (p = .02). Parafoveal DVD value was 52.58 ± 3.47 in group 1, 51.84 ± 2.23 in group 2, and 49.23 ± 3.38 in group 3 (p G1&3 = .001, p G2&3 = .02). Perifoveal DVD value was 47.92 ± 3.30 in group 1, 43.96 ± 4.19 in group 2, and 42.85 ± 2.98 in group 3 (p G1&2 = .02 and p G1&3 < .001). There were inverse correlations between diabetes duration, urea, creatinine, albumin, urinary sodium and some DVD values (p < .05, for all). Also, there were inverse correlations between parafoveal and perifoveal DVD values and MA (p = .002 and p = .031). Additionally, inverse correlations were determined between diabetes duration, creatinine, urea, serum Na and some CVD values (p < .05 for all).Conclusion: Decreased SVD and DVD values measured by OCTA in type-2 diabetic patients, whether they have mild DR or not, may be associated with MA causing early retinal microvascular changes. Keywords: Choriocapillaris vessel density; deep vessel density; diabetic nephropathy; diabetic retinopathy; microalbuminuria.
Kanser İçerikleri
Rahim Ağzı Kanseri
Yumurtalık Kanseri
Safra Yolları Kanseri
Rahim Kanseri
Rektum Kanseri
Tiroid Kanseri
Yemek Borusu (Özofagus) Kanseri
Testis Kanseri
Ağız Kanseri
Akciğer Kanseri
Cilt (Deri) Kanseri
Dil Kanseri
Gırtlak (Larinks) Kanseri
Göz Kanseri
Kanser Nedir? Kanser Belirtileri
Tükürük Bezi Kanseri
Karaciğer Kanseri
Kolon (Kalın Bağırsak) Kanseri
Lenf Kanseri
Lösemi
Meme Kanseri
Mesane Kanseri
Metastaz
Mide Kanseri
Multipl Miyelom
Pankreas Kanseri
Penis Kanseri
Prostat Kanseri